Parasite Helpful in Cancer Treatment : A deadly parasite responsible for the poor health of people with weak immunity and pregnant women Helpful in the treatment of cancer and many types of tumors (which can cause cancer) can be proved. The findings of this new study have been published in the ‘Journal for Immunotherapy Cancer’. published Has been done. Experts from the UK’s University of Nottingham and China’s Ningbo University and Shanxi Agricultural University have jointly conducted this research. Study has carried out.
Researchers say that a deadly parasite improves the effectiveness of treatment against certain types of tumors. It is also important for eliminating certain types of cancer and preventing tumor growth and prolonging the lifespan of patients.
In this new study, researchers revealed that this common parasite found worldwide makes cold tumors vulnerable. This type of tumor disrupts the work of strong immunity of the body, affecting the immune checkpoint blockade therapy. Researchers believe that this study can be useful in the treatment of various types of cancer.
Parasite infects warm blooded organisms
According to researchers from all three universities, the Toxoplasma gondii parasite is helpful in the treatment of cancer. It is a type of unicellular protozoa that infects warm-blooded animals. According to an estimate, this protozoa is found in about a third of the human population worldwide.
experiment on rats
Under this study, researchers first created a mutated strain of Toxoplasma gondii with limited growth potential. This experiment was done in cellular culture and on mice. This strain was able to modify the immune system of the host. To use in the treatment, the researchers injected the mutated parasite directly into the tumor. This not only caused an inflammatory response in solid tumors, but also had an effect on tumors located in the body of mice. They also found that tumor treatment was more effective in this procedure. Along with this, there was also a positive effect on immune checkpoint inhibitors. At the same time, the growth of cancerous tumors decreased and their lifespan also increased.
what the experts say
Associate Professor of the School of Veterinary Medicine and Science at the University of Nottingham and lead author of the research Dr. Honey Elsheikha (Dr Hany Elsheikha) Said that mutant mice models of Toxoplasma gondii have been used in the treatment of certain types of tumors in the past, but this recent experiment strengthened anti-tumor immunity with this strain, which was injected within the tumor and Checkpoint inhibition therapy was also found to be effective.